atmatma-japta-grha-vitta-janesu saktair
dusprapanaya guna-sanga-vivarjitaya
muktatmabhih sva-hrdaye paribhavitaya
jnanatmane bhagavate nama isvaraya
atma—the mind and body; atma-ja—sons and daughters; apta—friends and relatives; grha—home, community, society and nation; vitta—wealth; janesu—to various servants and assistants; saktaih—by those who are too attached; dusprapanaya—unto You, who are very difficult to achieve; guna-sanga—by the three modes of material nature; vivarjitaya—who are not contaminated; mukta-atmabhih—by persons who are already liberated; sva-hrdaye—within the core of the heart; paribhavitaya—unto You, who are always meditated upon; jnana-atmane—the reservoir of all enlightenment; bhagavate—unto the Supreme Personality of Godhead; namah—I offer my respectful obeisances; isvaraya—unto the supreme controller.
My Lord, those who are completely freed from material contamination always meditate upon You within the cores of their hearts. You are extremely difficult to attain for those like me who are too attached to mental concoction, home, relatives, friends, money, servants and assistants. You are the Supreme Personality of Godhead, uncontaminated by the modes of nature. You are the reservoir of all enlightenment, the supreme controller. I therefore offer my respectful obeisances unto You.
Although the Supreme Personality of Godhead comes into the material world, He is unaffected by the modes of material nature. This is confirmed in Isopanisad. Apapa-viddham: He is not contaminated. This same fact is described here. Guna-sanga-vivarjitaya. Although the Supreme Personality of Godhead appears as an incarnation within this material world, He is unaffected by the modes of material nature. As stated in Bhagavad-gita (9.11), avajananti mam mudha manusim tanum asritam: foolish men with insufficient knowledge deride the Personality of Godhead because He appears just like a human being. Therefore the Supreme Personality of Godhead can be understood only by the muktatma, the liberated soul. Muktatmabhih sva-hrdaye paribhavitaya: only the liberated person can constantly think of Krsna. Such a person is the greatest of all yogis.
yoginam api sarvesam
sraddhavan bhajate yo mam
sa me yuktatamo matah
“Of all yogis, he who always abides in Me with great faith, worshiping Me in transcendental loving service, is most intimately united with Me in yoga and is the highest of all.” (Bg. 6.47)

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