Anger is so detrimental that even a great personality like Daksa, out of anger, left the arena where Brahma was presiding and all the great sages and pious and saintly persons were assembled. All of them requested him not to leave, but, infuriated, he left, thinking that the auspicious place was not fit for him. Puffed up by his exalted position, he thought that no one was greater than he in argument. It appears that all the members of the assembly, including Lord Brahma, requested him not to be angry and leave their company, but in spite of all these requests, he left. That is the effect of cruel anger. In Bhagavad-gita, therefore, it is advised that one who desires to make tangible advancement in spiritual consciousness must avoid three thingslust, anger and the mode of passion. Actually we can see that lust, anger and passion make a man crazy, even though he be as great as Daksa. The very name Daksa suggests that he was expert in all material activities, but still, because of his aversion towards such a saintly personality as Siva, he was attacked by these three enemiesanger, lust and passion. Lord Caitanya, therefore, advised that one be very careful not to offend Vaisnavas. He compared offenses toward a Vaisnava to a mad elephant. As a mad elephant can do anything horrible, so when a person offends a Vaisnava he can perform any abominable action.