a-kāreṇocyate kṛṣṇaḥ sarva-lokaika-nāyakaḥ u-kāreṇocyate rādhā ma-kāro jīva-vācakaḥ

a-karenocyate krsnah
sarva-lokaika-nayakah
u-karenocyate radha
ma-karo jiva-vacakah
Omkara is a combination of the letters a, u and m. A-karenocyate krsnah: the letter a (a-kara) refers to Krsna, who is sarva-lokaika-nayakah, the master of all living entities and planets, material and spiritual. Nayaka means "leader." He is the supreme leader (nityo nityanam cetanas cetananam). The letter u (u-kara) indicates Srimati Radharani, the pleasure potency of Krsna, and m (ma-kara) indicates the living entities (jivas). Thus om is the complete combination of Krsna, His potency and His eternal servitors. In other words, omkara represents Krsna, His name, fame, pastimes, entourage, expansions, devotees, potencies and everything else pertaining to Him. Sarva-visva-dhama: omkara is the resting place of everything, just as Krsna is the resting place of everything (brahmano hi pratisthaham).
The Mayavadi philosophers consider many Vedic mantras to be the maha-vakya, or principal Vedic mantra, such as tattvamasi (Chandogya Upanisad, 6.8.7), idam sarvam yad ayam atma and brahmedam sarvam (Brhad-aranyaka Upanisad, 2.5.1), atmaivedam sarvam (Chandogya Upanisad, 7.25.2) and neha nanasti kincana (Katha Upanisad, 2.1.11). That is a great mistake. Only omkara is the maha-vakya. All these other mantras which the Mayavadis accept as the maha-vakya are only incidental. They cannot be taken as the maha-vakya, or maha-mantra. The mantra tattvamasi indicates only a partial understanding of the Vedas, unlike omkara, which represents the full understanding of the Vedas. Therefore the transcendental sound which includes all Vedic knowledge is omkara (pranava).
Aside from omkara, none of the words uttered by the followers of Saṅkaracarya can be considered the maha-vakya. They are merely passing remarks. Saṅkaracarya, however, has never stressed chanting of the maha-vakya omkara; he has accepted only tattvamasi as the maha-vakya. Imagining the living entity to be God, he has misrepresented all the mantras of the Vedanta-sutra with the motive of proving that there is no separate existence of the living entities and the Supreme Absolute Truth. This is similar to the politician's attempt to prove nonviolence from Bhagavad-gita. Krsna is violent to demons, and to attempt to prove that Krsna is not violent is ultimately to deny Krsna. As such explanations of Bhagavad-gita are absurd, so also is Saṅkaracarya's explanation of Vedanta-sutra, and no sane and reasonable man will accept it. At present, however, Vedanta-sutra is misrepresented not only by the so-called Vedantis but also by other unscrupulous persons who are so degraded that they even recommend that sannyasis eat meat, fish and eggs. In this way, the so-called followers of Saṅkara, the impersonalist Mayavadis, are sinking lower and lower. How can these degraded men explain Vedanta-sutra, which is the essence of all Vedic literature?
Lord Sri Caitanya Mahaprabhu has declared, mayavadi-bhasya sunile haya sarva-nasa: anyone who hears commentary on the Vedanta-sutra from the Mayavada school is completely doomed. As explained in Bhagavad-gita, vedais ca sarvair aham eva vedyah: all Vedic literature aims to understand Krsna (Bg. 15.15). Mayavada philosophy, however, has deviated everyone from Krsna. Therefore there is a great need for the Krsna consciousness movement all over the world to save the world from degradation. Every intelligent and sane man must abandon the philosophical explanation of the Mayavadis and accept the explanation of Vaisnava acaryas. One should read Bhagavad-gita As It Is to try to understand the real purpose of the Vedas.