pāvanāni manīṣiṇām

yajna-sacrifice; dana-charity; tapah-penance; karma-activities; na-never; tyajyam-to be given up; karyam-must be done; eva-certainly; tat-that; yajnah-sacrifice; danam-charity; tapah-penance; ca-also; eva-certainly; pavanani-purifying; manisinam-even of the great souls.